aztreonam
TL;DR: aztreonam (CAS 112136-28-4) is a chemical compound with molecular formula C13H17N5O8S2 and molecular weight 435.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(E)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
Also Known As: aztreonam, Azactam, rac-Aztreonam E Isomer, K379, I05-0077
| Molecular Formula | C13H17N5O8S2 |
|---|---|
| Molecular Weight | 435.05 g/mol |
| LogP | -1.1725 |
| Topological Polar Surface Area | 201.58 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 7 |
| Exact Mass | 435.05185 |
| Heavy Atoms | 28 |
| Complexity | 953.88513 |
Chemical Identifiers
| CAS Number | 112136-28-4 |
|---|---|
| SMILES | CC1C(C(=O)N1S(=O)(=O)O)NC(=O)/C(=N/OC(C)(C)C(=O)O)/C2=CSC(=N2)N |
Product Overview
aztreonam (CAS 112136-28-4), with molecular formula C13H17N5O8S2 and molecular weight 435.05 g/mol. IUPAC: 2-[(E)-[1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid.
Chemical Property Profile of aztreonam
Property Insights of aztreonam
The XLogP value of -1.1725 indicates that aztreonam is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 201.58 Ų indicates high polarity, suggesting aztreonam may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, aztreonam has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of aztreonam?
The CAS number of aztreonam is 112136-28-4.
What is the molecular formula of aztreonam?
The molecular formula of aztreonam is C13H17N5O8S2.
What is the molecular weight of aztreonam?
The molecular weight of aztreonam is 435.05 g/mol.
Where can I buy aztreonam?
You can request a quote for aztreonam directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for aztreonam?
Yes, KEHONG BIO provides custom synthesis services for aztreonam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.