L 657743
TL;DR: L 657743 (CAS 111466-41-2) is a chemical compound with molecular formula C20H25N3O2 and molecular weight 339.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,12bS)-1',3'-dimethylspiro[1,3,4,6,7,12b-hexahydro-[1]benzofuro[2,3-a]quinolizine-2,4'-1,3-diazinane]-2'-one
Also Known As: MK-912 FREE BASE, L-657743 Free, MK 912, MK912, L-657,743
| Molecular Formula | C20H25N3O2 |
|---|---|
| Molecular Weight | 339.19 g/mol |
| LogP | 2.3 |
| Topological Polar Surface Area | 39.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 339.19467 |
| Heavy Atoms | 25 |
| Complexity | 555.0 |
Chemical Identifiers
| CAS Number | 111466-41-2 |
|---|---|
| SMILES | CN1CC[C@]2(CCN3CCC4=C([C@@H]3C2)OC5=CC=CC=C45)N(C1=O)C |
| InChIKey | JRDUBBHIPPPSLP-OXJNMPFZSA-N |
Product Overview
L 657743 (CAS 111466-41-2), with molecular formula C20H25N3O2 and molecular weight 339.19 g/mol. IUPAC: (2S,12bS)-1',3'-dimethylspiro[1,3,4,6,7,12b-hexahydro-[1]benzofuro[2,3-a]quinolizine-2,4'-1,3-diazinane]-2'-one.
Chemical Property Profile of L 657743
Property Insights of L 657743
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L 657743. With a topological polar surface area (TPSA) of 39.9 Ų, L 657743 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, L 657743 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of L 657743?
The CAS number of L 657743 is 111466-41-2.
What is the molecular formula of L 657743?
The molecular formula of L 657743 is C20H25N3O2.
What is the molecular weight of L 657743?
The molecular weight of L 657743 is 339.19 g/mol.
Where can I buy L 657743?
You can request a quote for L 657743 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for L 657743?
Yes, KEHONG BIO provides custom synthesis services for L 657743 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.