2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O structure

2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O

TL;DR: 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O (CAS 111218-79-2) is a chemical compound with molecular formula C22H29Cl3N4O4 and molecular weight 518.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[3-[(2-chloro-6,7-dimethoxyquinazolin-4-yl)amino]phenoxy]-3-(propan-2-ylamino)propan-2-ol;dihydrochloride

Also Known As: 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O, 2-Propanol, 1-(3-((2-chloro-6,7-dimethoxy-4-quinazolinyl)amino)phenoxy)-3-((1-methylethyl)amino)-, dihydrochloride, hydrate, 1-[3-[(2-chloro-6,7-dimethoxyquinazolin-4-yl)amino]phenoxy]-3-(propan-2-ylamino)propan-2-ol dihydrochloride, 1-{3-[(2-Chloro-6,7-dimethoxyquinazolin-4(3H)-ylidene)amino]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol--hydrogen chloride (1/2), RefChem:265732

CAS: 111218-79-2
Molecular Formula C22H29Cl3N4O4
Molecular Weight 518.13 g/mol
LogP 4.6253
Topological Polar Surface Area 97.76 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 8
Rotatable Bonds 10
Exact Mass 518.1254
Heavy Atoms 33
Complexity 1039.9387

Chemical Identifiers

CAS Number 111218-79-2
SMILES CC(C)NCC(COC1=CC=CC(=C1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)Cl)O.Cl.Cl

Product Overview

2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O (CAS 111218-79-2), with molecular formula C22H29Cl3N4O4 and molecular weight 518.13 g/mol. IUPAC: 1-[3-[(2-chloro-6,7-dimethoxyquinazolin-4-yl)amino]phenoxy]-3-(propan-2-ylamino)propan-2-ol;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O

XLogP
4.6253
TPSA (Topological Polar Surface Area)
97.76
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
8
Rotatable Bonds
10
Heavy Atoms
33
Complexity
1039.9387
Exact Mass
518.1254
Monoisotopic Mass
518.1254
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O

The XLogP value of 4.6253 indicates that 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.76 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O. Following Lipinski's Rule of Five, 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O?

The CAS number of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O is 111218-79-2.

What is the molecular formula of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O?

The molecular formula of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O is C22H29Cl3N4O4.

What is the molecular weight of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O?

The molecular weight of 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O is 518.13 g/mol.

Where can I buy 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O?

You can request a quote for 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O?

Yes, KEHONG BIO provides custom synthesis services for 2-Chloro-4-(3-(3'-isopropylamino-2'-oxopropoxy)phenylamino)-6,7-dimethoxyquinazoline 2HCl H2O and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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