Amlodipine Impurity 8
TL;DR: Amlodipine Impurity 8 (CAS 110962-94-2) is a chemical compound with molecular formula C19H18Cl2N2O4 and molecular weight 408.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-O-(2-cyanoethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Amlodipine Impurity 8, Clevidipine Impurity G, 4-(2,3-Dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-cyano-ethyl) ester 5-methyl ester, Clevidipine butyrate Impurity 6, Clevidipine butyrate Impurity 7
| Molecular Formula | C19H18Cl2N2O4 |
|---|---|
| Molecular Weight | 408.06 g/mol |
| LogP | 3.85808 |
| Topological Polar Surface Area | 88.42 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 408.06436 |
| Heavy Atoms | 27 |
| Complexity | 884.1861 |
Chemical Identifiers
| CAS Number | 110962-94-2 |
|---|---|
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCCC#N)C2=C(C(=CC=C2)Cl)Cl)C(=O)OC |
Product Overview
Amlodipine Impurity 8 (CAS 110962-94-2), with molecular formula C19H18Cl2N2O4 and molecular weight 408.06 g/mol. IUPAC: 5-O-(2-cyanoethyl) 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate.
Chemical Property Profile of Amlodipine Impurity 8
Property Insights of Amlodipine Impurity 8
The XLogP value of 3.85808 indicates that Amlodipine Impurity 8 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.42 Ų falls within the moderate polarity range, balancing permeability and solubility for Amlodipine Impurity 8. Following Lipinski's Rule of Five, Amlodipine Impurity 8 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amlodipine Impurity 8?
The CAS number of Amlodipine Impurity 8 is 110962-94-2.
What is the molecular formula of Amlodipine Impurity 8?
The molecular formula of Amlodipine Impurity 8 is C19H18Cl2N2O4.
What is the molecular weight of Amlodipine Impurity 8?
The molecular weight of Amlodipine Impurity 8 is 408.06 g/mol.
Where can I buy Amlodipine Impurity 8?
You can request a quote for Amlodipine Impurity 8 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amlodipine Impurity 8?
Yes, KEHONG BIO provides custom synthesis services for Amlodipine Impurity 8 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.