7-Ethyl-10-hydroxy camptothecin, (rac)-
TL;DR: 7-Ethyl-10-hydroxy camptothecin, (rac)- (CAS 110714-48-2) is a chemical compound with molecular formula C22H20N2O5 and molecular weight 392.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione
Also Known As: 7-Ethyl-10-hydroxycamptothecin, Camptothecin analog, Camptothecin Impurity 21, SN-38-d3, 7-Ethyl-10-hydroxy camptothecin
| Molecular Formula | C22H20N2O5 |
|---|---|
| Molecular Weight | 392.14 g/mol |
| LogP | 2.3476 |
| Topological Polar Surface Area | 101.65 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 392.1372 |
| Heavy Atoms | 29 |
| Complexity | 1276.6583 |
Chemical Identifiers
| CAS Number | 110714-48-2 |
|---|---|
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O |
Product Overview
7-Ethyl-10-hydroxy camptothecin, (rac)- (CAS 110714-48-2), with molecular formula C22H20N2O5 and molecular weight 392.14 g/mol. IUPAC: 10,19-diethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 7-Ethyl-10-hydroxy camptothecin, (rac)-
Property Insights of 7-Ethyl-10-hydroxy camptothecin, (rac)-
The XLogP value of 2.3476 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-Ethyl-10-hydroxy camptothecin, (rac)-. The TPSA of 101.65 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-Ethyl-10-hydroxy camptothecin, (rac)-. Following Lipinski's Rule of Five, 7-Ethyl-10-hydroxy camptothecin, (rac)- has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-Ethyl-10-hydroxy camptothecin, (rac)-?
The CAS number of 7-Ethyl-10-hydroxy camptothecin, (rac)- is 110714-48-2.
What is the molecular formula of 7-Ethyl-10-hydroxy camptothecin, (rac)-?
The molecular formula of 7-Ethyl-10-hydroxy camptothecin, (rac)- is C22H20N2O5.
What is the molecular weight of 7-Ethyl-10-hydroxy camptothecin, (rac)-?
The molecular weight of 7-Ethyl-10-hydroxy camptothecin, (rac)- is 392.14 g/mol.
Where can I buy 7-Ethyl-10-hydroxy camptothecin, (rac)-?
You can request a quote for 7-Ethyl-10-hydroxy camptothecin, (rac)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-Ethyl-10-hydroxy camptothecin, (rac)-?
Yes, KEHONG BIO provides custom synthesis services for 7-Ethyl-10-hydroxy camptothecin, (rac)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.