Meclozine Dihydrochloride
TL;DR: Meclozine Dihydrochloride (CAS 1104-22-9) is a chemical compound with molecular formula C25H29Cl3N2 and molecular weight 462.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;dihydrochloride
Also Known As: Meclizine dihydrochloride, Bonamine, Meclozine dihydrochloride, Meclizine hydrochloride, Duremesin
| Molecular Formula | C25H29Cl3N2 |
|---|---|
| Molecular Weight | 462.14 g/mol |
| LogP | 6.4 |
| Topological Polar Surface Area | 6.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 462.13962 |
| Heavy Atoms | 30 |
| Complexity | 447.0 |
Chemical Identifiers
| CAS Number | 1104-22-9 |
|---|---|
| SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl |
| InChIKey | VCTHNOIYJIXQLV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Meclozine Dihydrochloride (CAS 1104-22-9), with molecular formula C25H29Cl3N2 and molecular weight 462.14 g/mol. IUPAC: 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]piperazine;dihydrochloride.
Chemical Property Profile of Meclozine Dihydrochloride
Property Insights of Meclozine Dihydrochloride
The XLogP value of 6.4 indicates that Meclozine Dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Meclozine Dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Meclozine Dihydrochloride has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Meclozine Dihydrochloride?
The CAS number of Meclozine Dihydrochloride is 1104-22-9.
What is the molecular formula of Meclozine Dihydrochloride?
The molecular formula of Meclozine Dihydrochloride is C25H29Cl3N2.
What is the molecular weight of Meclozine Dihydrochloride?
The molecular weight of Meclozine Dihydrochloride is 462.14 g/mol.
Where can I buy Meclozine Dihydrochloride?
You can request a quote for Meclozine Dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Meclozine Dihydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Meclozine Dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.