Quinolone analog 8
TL;DR: Quinolone analog 8 (CAS 110236-79-8) is a chemical compound with molecular formula C18H20F2N4O3 and molecular weight 378.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-amino-1-cyclopropyl-6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
Also Known As: Quinolone analog 8, Epidermal Growth Factor Receptor Peptide (985-996), A0696/0032447, 5-amino-1-cyclopropyl-6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-5-amino-7-(4-methyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid
| Molecular Formula | C18H20F2N4O3 |
|---|---|
| Molecular Weight | 378.15 g/mol |
| LogP | 1.6468 |
| Topological Polar Surface Area | 91.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 378.15036 |
| Heavy Atoms | 27 |
| Complexity | 1008.30457 |
Chemical Identifiers
| CAS Number | 110236-79-8 |
|---|---|
| SMILES | CN1CCN(CC1)C2=C(C(=C3C(=C2F)N(C=C(C3=O)C(=O)O)C4CC4)N)F |
Product Overview
Quinolone analog 8 (CAS 110236-79-8), with molecular formula C18H20F2N4O3 and molecular weight 378.15 g/mol. IUPAC: 5-amino-1-cyclopropyl-6,8-difluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid.
Chemical Property Profile of Quinolone analog 8
Property Insights of Quinolone analog 8
The XLogP value of 1.6468 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Quinolone analog 8. The TPSA of 91.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Quinolone analog 8. Following Lipinski's Rule of Five, Quinolone analog 8 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Quinolone analog 8?
The CAS number of Quinolone analog 8 is 110236-79-8.
What is the molecular formula of Quinolone analog 8?
The molecular formula of Quinolone analog 8 is C18H20F2N4O3.
What is the molecular weight of Quinolone analog 8?
The molecular weight of Quinolone analog 8 is 378.15 g/mol.
Where can I buy Quinolone analog 8?
You can request a quote for Quinolone analog 8 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Quinolone analog 8?
Yes, KEHONG BIO provides custom synthesis services for Quinolone analog 8 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.