Phleomycin
TL;DR: Phleomycin (CAS 11006-33-0) is a chemical compound with molecular formula C51H75N17O21S2 and molecular weight 1325.48 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2S,3R,4R,5S)-4-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)-3-methyloxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-oxobutanoyl]amino]ethyl]-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxamide
Also Known As: Phleomycin, Phleomycins, Phleomycin complex, Phleomycin, 95%+, Phleomycin - 25MG 25mg
| Molecular Formula | C51H75N17O21S2 |
|---|---|
| Molecular Weight | 1325.48 g/mol |
| LogP | -10.2 |
| Topological Polar Surface Area | 702.0 Ų |
| Hydrogen Bond Donors | 20 |
| Hydrogen Bond Acceptors | 31 |
| Rotatable Bonds | 31 |
| Exact Mass | 1325.4764 |
| Heavy Atoms | 91 |
| Complexity | 2650.0 |
Chemical Identifiers
| CAS Number | 11006-33-0 |
|---|---|
| SMILES | CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)O[C@H]3[C@@]([C@H]([C@@H]([C@@H](O3)CO)O)O)(C)O[C@H]4[C@@H]([C@]([C@H](C(O4)CO)O)(C(=O)N)O)O)C(=O)NC(C)C(C(C)C(=O)NC(C(=O)C)C(=O)NCCC5=NC(CS5)C6=NC(=CS6)C(=O)N)O |
| InChIKey | QRBLKGHRWFGINE-UGWAGOLRSA-N |
Product Overview
Phleomycin (CAS 11006-33-0), with molecular formula C51H75N17O21S2 and molecular weight 1325.48 g/mol. IUPAC: 2-[2-[2-[[2-[[4-[[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2S,3R,4R,5S)-4-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)-3-methyloxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-oxobutanoyl]amino]ethyl]-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazole-4-carboxamide.
Chemical Property Profile of Phleomycin
Property Insights of Phleomycin
The XLogP value of -10.2 indicates that Phleomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 702.0 Ų indicates high polarity, suggesting Phleomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Phleomycin has 20 hydrogen bond donor(s) and 31 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Phleomycin?
The CAS number of Phleomycin is 11006-33-0.
What is the molecular formula of Phleomycin?
The molecular formula of Phleomycin is C51H75N17O21S2.
What is the molecular weight of Phleomycin?
The molecular weight of Phleomycin is 1325.48 g/mol.
Where can I buy Phleomycin?
You can request a quote for Phleomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Phleomycin?
Yes, KEHONG BIO provides custom synthesis services for Phleomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.