1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride
TL;DR: 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride (CAS 109377-01-7) is a chemical compound with molecular formula C25H37Cl2N3O3 and molecular weight 497.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(2-hydroxy-3-naphthalen-1-yloxypropyl)piperazin-1-yl]-3-piperidin-1-ylpropan-1-one;dihydrochloride
Also Known As: 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride, 1-Piperazineethanol, alpha-((1-naphthalenyloxy)methyl)-4-(1-oxo-3-(1-piperidinyl)propyl)-, dihydrochloride, alpha-((1-Naphthalenyloxy)methyl)-4-(1-oxo-3-(1-piperidinyl)propyl)-1-piperazineethanol 2HCl, 1-(4-{2-Hydroxy-3-[(naphthalen-1-yl)oxy]propyl}piperazin-1-yl)-3-(piperidin-1-yl)propan-1-one--hydrogen chloride (1/2), 1-[4-(2-hydroxy-3-naphthalen-1-yloxypropyl)piperazin-1-yl]-3-piperidin-1-ylpropan-1-one dihydrochloride
| Molecular Formula | C25H37Cl2N3O3 |
|---|---|
| Molecular Weight | 497.22 g/mol |
| LogP | 3.4433 |
| Topological Polar Surface Area | 56.25 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 497.2212 |
| Heavy Atoms | 33 |
| Complexity | 850.41095 |
Chemical Identifiers
| CAS Number | 109377-01-7 |
|---|---|
| SMILES | C1CCN(CC1)CCC(=O)N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O.Cl.Cl |
Product Overview
1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride (CAS 109377-01-7), with molecular formula C25H37Cl2N3O3 and molecular weight 497.22 g/mol. IUPAC: 1-[4-(2-hydroxy-3-naphthalen-1-yloxypropyl)piperazin-1-yl]-3-piperidin-1-ylpropan-1-one;dihydrochloride.
Chemical Property Profile of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride
Property Insights of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride
The XLogP value of 3.4433 indicates that 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.25 Ų, 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride?
The CAS number of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride is 109377-01-7.
What is the molecular formula of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride?
The molecular formula of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride is C25H37Cl2N3O3.
What is the molecular weight of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride?
The molecular weight of 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride is 497.22 g/mol.
Where can I buy 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride?
You can request a quote for 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-Piperidinopropionyl)-4-(2-hydroxy-3-(alpha-naphthyloxy)propyl)piperazine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.