PC-766B structure

PC-766B

TL;DR: PC-766B (CAS 108375-77-5) is a chemical compound with molecular formula C43H68O12 and molecular weight 776.47 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(3E,5Z,7R,8S,9S,11Z,13Z,15S,16R)-16-[(3R,4S)-4-[(2R,4R,5S,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one

Also Known As: PC-766B, PC 766B, (3E,5Z,7R,8S,9S,11Z,13Z,15S,16R)-16-[(3R,4S)-4-[(2R,4R,5S,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one, 5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one, Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-((1S,2R,3S)-3-((2R,4R,5S,6R)-4-((2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy)tetrahydro-2-hydroxy-5-methyl-6-((1E,3E)-1,3-pentadienyl)-2H-pyran-2-yl)-2-hydroxy-1-methylbutyl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-

CAS: 108375-77-5
Molecular Formula C43H68O12
Molecular Weight 776.47 g/mol
LogP 5.05
Topological Polar Surface Area 173.6 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 12
Rotatable Bonds 10
Exact Mass 776.47107
Heavy Atoms 55
Complexity 1405.6174

Chemical Identifiers

CAS Number 108375-77-5
SMILES C/C=C/C=C/[C@@H]1[C@H]([C@@H](C[C@@](O1)([C@@H](C)[C@@H](C(C)[C@@H]2[C@H](/C=C\C=C(/C[C@@H]([C@@H]([C@@H](/C=C(\C=C(/C(=O)O2)\OC)/C)C)O)C)\C)OC)O)O)O[C@@H]3C[C@H]([C@@H]([C@H](O3)C)O)O)C

Product Overview

PC-766B (CAS 108375-77-5), with molecular formula C43H68O12 and molecular weight 776.47 g/mol. IUPAC: (3E,5Z,7R,8S,9S,11Z,13Z,15S,16R)-16-[(3R,4S)-4-[(2R,4R,5S,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxy-5-methyl-6-[(1E,3E)-penta-1,3-dienyl]oxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PC-766B

XLogP
5.05
TPSA (Topological Polar Surface Area)
173.6
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
12
Rotatable Bonds
10
Heavy Atoms
55
Complexity
1405.6174
Exact Mass
776.47107
Monoisotopic Mass
776.47107
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PC-766B

The XLogP value of 5.05 indicates that PC-766B is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 173.6 Ų indicates high polarity, suggesting PC-766B may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, PC-766B has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PC-766B?

The CAS number of PC-766B is 108375-77-5.

What is the molecular formula of PC-766B?

The molecular formula of PC-766B is C43H68O12.

What is the molecular weight of PC-766B?

The molecular weight of PC-766B is 776.47 g/mol.

Where can I buy PC-766B?

You can request a quote for PC-766B directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PC-766B?

Yes, KEHONG BIO provides custom synthesis services for PC-766B and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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