Gevotroline structure

Gevotroline

TL;DR: Gevotroline (CAS 107266-06-8) is a chemical compound with molecular formula C19H20FN3 and molecular weight 309.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-fluoro-2-(3-pyridin-3-ylpropyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole

Also Known As: GEVOTROLINE, Gevotrolina, Gevotrolinum, Gevotroline [INN], Gevotrolinum [INN-Latin]

CAS: 107266-06-8
Molecular Formula C19H20FN3
Molecular Weight 309.16 g/mol
LogP 3.3
Topological Polar Surface Area 31.9 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 309.16412
Heavy Atoms 23
Complexity 391.0

Chemical Identifiers

CAS Number 107266-06-8
SMILES C1CN(CC2=C1NC3=C2C=C(C=C3)F)CCCC4=CN=CC=C4
InChIKey RZXHTPCHKSYGIB-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (8 patents) Pharmaceutical Intermediates (27 patents)

Product Overview

Gevotroline (CAS 107266-06-8), with molecular formula C19H20FN3 and molecular weight 309.16 g/mol. IUPAC: 8-fluoro-2-(3-pyridin-3-ylpropyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Gevotroline

XLogP
3.3
TPSA (Topological Polar Surface Area)
31.9
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
23
Complexity
391.0
Exact Mass
309.16412
Monoisotopic Mass
309.16412
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Gevotroline

The XLogP value of 3.3 indicates that Gevotroline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 31.9 Ų, Gevotroline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Gevotroline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Gevotroline?

The CAS number of Gevotroline is 107266-06-8.

What is the molecular formula of Gevotroline?

The molecular formula of Gevotroline is C19H20FN3.

What is the molecular weight of Gevotroline?

The molecular weight of Gevotroline is 309.16 g/mol.

Where can I buy Gevotroline?

You can request a quote for Gevotroline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Gevotroline?

Yes, KEHONG BIO provides custom synthesis services for Gevotroline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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