OPC 8490 free base structure

OPC 8490 free base

TL;DR: OPC 8490 free base (CAS 106752-32-3) is a chemical compound with molecular formula C24H27N3O3 and molecular weight 405.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

6-[4-(4-oxo-4-phenylbutyl)piperazine-1-carbonyl]-3,4-dihydro-1H-quinolin-2-one

Also Known As: OPC 8490 free base, Piperazine, 1-(4-oxo-4-phenylbutyl)-4-[(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)carbonyl]-, 6-[4-(4-oxo-4-phenyl-butyl)piperazine-1-carbonyl]-3,4-dihydro-1H-quinolin-2-one, 6-[4-(4-oxo-4-phenylbutyl)piperazine-1-carbonyl]-3,4-dihydro-1H-quinolin-2-one

CAS: 106752-32-3
Molecular Formula C24H27N3O3
Molecular Weight 405.21 g/mol
LogP 2.0
Topological Polar Surface Area 69.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 405.20523
Heavy Atoms 30
Complexity 623.0

Chemical Identifiers

CAS Number 106752-32-3
SMILES C1CC(=O)NC2=C1C=C(C=C2)C(=O)N3CCN(CC3)CCCC(=O)C4=CC=CC=C4
InChIKey VCMKKOPAGZSVOM-UHFFFAOYSA-N

Product Overview

OPC 8490 free base (CAS 106752-32-3), with molecular formula C24H27N3O3 and molecular weight 405.21 g/mol. IUPAC: 6-[4-(4-oxo-4-phenylbutyl)piperazine-1-carbonyl]-3,4-dihydro-1H-quinolin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of OPC 8490 free base

XLogP
2.0
TPSA (Topological Polar Surface Area)
69.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
30
Complexity
623.0
Exact Mass
405.20523
Monoisotopic Mass
405.20523
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of OPC 8490 free base

The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for OPC 8490 free base. The TPSA of 69.7 Ų falls within the moderate polarity range, balancing permeability and solubility for OPC 8490 free base. Following Lipinski's Rule of Five, OPC 8490 free base has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of OPC 8490 free base?

The CAS number of OPC 8490 free base is 106752-32-3.

What is the molecular formula of OPC 8490 free base?

The molecular formula of OPC 8490 free base is C24H27N3O3.

What is the molecular weight of OPC 8490 free base?

The molecular weight of OPC 8490 free base is 405.21 g/mol.

Where can I buy OPC 8490 free base?

You can request a quote for OPC 8490 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for OPC 8490 free base?

Yes, KEHONG BIO provides custom synthesis services for OPC 8490 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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