Sertindole
TL;DR: Sertindole (CAS 106516-24-9) is a chemical compound with molecular formula C24H26ClFN4O and molecular weight 440.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Also Known As: Serdolect, SerLect, Sertindol, Sertindolum, zerdol
| Molecular Formula | C24H26ClFN4O |
|---|---|
| Molecular Weight | 440.18 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 40.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 440.17792 |
| Heavy Atoms | 31 |
| Complexity | 623.0 |
| Solubility | 9.63e-03 g/L |
Chemical Identifiers
| CAS Number | 106516-24-9 |
|---|---|
| SMILES | C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O |
| InChIKey | GZKLJWGUPQBVJQ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Sertindole (CAS 106516-24-9), with molecular formula C24H26ClFN4O and molecular weight 440.18 g/mol. IUPAC: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one.
Chemical Property Profile of Sertindole
Property Insights of Sertindole
The XLogP value of 4.1 indicates that Sertindole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, Sertindole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Sertindole has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sertindole?
The CAS number of Sertindole is 106516-24-9.
What is the molecular formula of Sertindole?
The molecular formula of Sertindole is C24H26ClFN4O.
What is the molecular weight of Sertindole?
The molecular weight of Sertindole is 440.18 g/mol.
Where can I buy Sertindole?
You can request a quote for Sertindole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sertindole?
Yes, KEHONG BIO provides custom synthesis services for Sertindole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.