Ro 22-9194 structure

Ro 22-9194

TL;DR: Ro 22-9194 (CAS 106134-33-2) is a chemical compound with molecular formula C19H27Cl2N3O and molecular weight 383.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-amino-N-(2,6-dimethylphenyl)-N-(3-pyridin-3-ylpropyl)propanamide;dihydrochloride

Also Known As: Milacainide, Ro 22-9194, Ro-22-9194, Tox21_113250, 2-Amino-N-(2,6-dimethylphenyl)-N-(3-(3-pyridyl)propyl)propionamide

CAS: 106134-33-2
Molecular Formula C19H27Cl2N3O
Molecular Weight 383.15 g/mol
LogP 3.85504
Topological Polar Surface Area 59.2 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 3
Rotatable Bonds 6
Exact Mass 383.1531
Heavy Atoms 25
Complexity 364.0

Chemical Identifiers

CAS Number 106134-33-2
SMILES CC1=C(C(=CC=C1)C)N(CCCC2=CN=CC=C2)C(=O)C(C)N.Cl.Cl
InChIKey VLIYADXYDUEILX-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (10 patents) Pharmaceutical Intermediates (4 patents)

Product Overview

Ro 22-9194 (CAS 106134-33-2), with molecular formula C19H27Cl2N3O and molecular weight 383.15 g/mol. IUPAC: 2-amino-N-(2,6-dimethylphenyl)-N-(3-pyridin-3-ylpropyl)propanamide;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ro 22-9194

XLogP
3.85504
TPSA (Topological Polar Surface Area)
59.2
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
3
Rotatable Bonds
6
Heavy Atoms
25
Complexity
364.0
Exact Mass
383.1531
Monoisotopic Mass
383.1531
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ro 22-9194

The XLogP value of 3.85504 indicates that Ro 22-9194 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.2 Ų, Ro 22-9194 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ro 22-9194 has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ro 22-9194?

The CAS number of Ro 22-9194 is 106134-33-2.

What is the molecular formula of Ro 22-9194?

The molecular formula of Ro 22-9194 is C19H27Cl2N3O.

What is the molecular weight of Ro 22-9194?

The molecular weight of Ro 22-9194 is 383.15 g/mol.

Where can I buy Ro 22-9194?

You can request a quote for Ro 22-9194 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ro 22-9194?

Yes, KEHONG BIO provides custom synthesis services for Ro 22-9194 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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