YM 16457 structure

YM 16457

TL;DR: YM 16457 (CAS 105980-35-6) is a chemical compound with molecular formula C16H17N5O5S4 and molecular weight 487.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(1,3-dithiolan-2-yl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Also Known As: YM 16457, (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(1,3-dithiolan-2-yl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(1,3-dithiolan-2-yl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7beta-[[(Z)-(2-Aminothiazol-4-yl)(methoxyimino)acetyl]amino]-3-(1,3-dithiolan-2-yl)cepham-3-ene-4-carboxylic acid

CAS: 105980-35-6
Molecular Formula C16H17N5O5S4
Molecular Weight 487.01 g/mol
LogP 0.6205
Topological Polar Surface Area 147.21 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 11
Rotatable Bonds 6
Exact Mass 487.01126
Heavy Atoms 30
Complexity 957.57715

Chemical Identifiers

CAS Number 105980-35-6
SMILES CO/N=C(/C1=CSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C4SCCS4)C(=O)O

Product Overview

YM 16457 (CAS 105980-35-6), with molecular formula C16H17N5O5S4 and molecular weight 487.01 g/mol. IUPAC: (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(1,3-dithiolan-2-yl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of YM 16457

XLogP
0.6205
TPSA (Topological Polar Surface Area)
147.21
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
11
Rotatable Bonds
6
Heavy Atoms
30
Complexity
957.57715
Exact Mass
487.01126
Monoisotopic Mass
487.01126
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of YM 16457

The XLogP value of 0.6205 suggests moderate lipophilicity, balancing water solubility and membrane permeability for YM 16457. The TPSA of 147.21 Ų indicates high polarity, suggesting YM 16457 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, YM 16457 has 3 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of YM 16457?

The CAS number of YM 16457 is 105980-35-6.

What is the molecular formula of YM 16457?

The molecular formula of YM 16457 is C16H17N5O5S4.

What is the molecular weight of YM 16457?

The molecular weight of YM 16457 is 487.01 g/mol.

Where can I buy YM 16457?

You can request a quote for YM 16457 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for YM 16457?

Yes, KEHONG BIO provides custom synthesis services for YM 16457 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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