14,15-Methylene estradiol
TL;DR: 14,15-Methylene estradiol (CAS 105455-76-3) is a chemical compound with molecular formula C19H24O2 and molecular weight 284.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,2S,6S,7S,10S)-7-methylpentacyclo[8.8.0.02,4.02,7.011,16]octadeca-11(16),12,14-triene-6,14-diol
Also Known As: 14,15-Methylene estradiol, Sts 661, 14alpha,15alpha-methylene estradiol, KST-1A0462, J-824
| Molecular Formula | C19H24O2 |
|---|---|
| Molecular Weight | 284.18 g/mol |
| LogP | 4.0 |
| Topological Polar Surface Area | 40.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 284.17764 |
| Heavy Atoms | 21 |
| Complexity | 462.0 |
Chemical Identifiers
| CAS Number | 105455-76-3 |
|---|---|
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@]14CC4C[C@@H]2O)CCC5=C3C=CC(=C5)O |
| InChIKey | PVNKGPKPHWVGIN-YVCKVCSPSA-N |
Product Overview
14,15-Methylene estradiol (CAS 105455-76-3), with molecular formula C19H24O2 and molecular weight 284.18 g/mol. IUPAC: (1R,2S,6S,7S,10S)-7-methylpentacyclo[8.8.0.02,4.02,7.011,16]octadeca-11(16),12,14-triene-6,14-diol.
Chemical Property Profile of 14,15-Methylene estradiol
Property Insights of 14,15-Methylene estradiol
The XLogP value of 4.0 indicates that 14,15-Methylene estradiol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.5 Ų, 14,15-Methylene estradiol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 14,15-Methylene estradiol has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 14,15-Methylene estradiol?
The CAS number of 14,15-Methylene estradiol is 105455-76-3.
What is the molecular formula of 14,15-Methylene estradiol?
The molecular formula of 14,15-Methylene estradiol is C19H24O2.
What is the molecular weight of 14,15-Methylene estradiol?
The molecular weight of 14,15-Methylene estradiol is 284.18 g/mol.
Where can I buy 14,15-Methylene estradiol?
You can request a quote for 14,15-Methylene estradiol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 14,15-Methylene estradiol?
Yes, KEHONG BIO provides custom synthesis services for 14,15-Methylene estradiol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.