7-O-Ribofuranosyladriamycinone
TL;DR: 7-O-Ribofuranosyladriamycinone (CAS 105445-03-2) is a chemical compound with molecular formula C26H26O13 and molecular weight 546.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(7R,9S)-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
Also Known As: 7-O-Rfadm, 7-O-Ribofuranosyladriamycinone, 7-O-(D-Ribofuranosyl)adriamycinone, bis(2-hydroxyethyl)-dimethylazanium,iodide, (7R,9S)-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
| Molecular Formula | C26H26O13 |
|---|---|
| Molecular Weight | 546.14 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 221.0 Ų |
| Hydrogen Bond Donors | 7 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 6 |
| Exact Mass | 546.1373 |
| Heavy Atoms | 39 |
| Complexity | 973.0 |
Chemical Identifiers
| CAS Number | 105445-03-2 |
|---|---|
| SMILES | COC1=CC=CC2=C1C(=O)C3=C(C4=C(C[C@](C[C@H]4O[C@H]5[C@@H]([C@@H]([C@H](O5)CO)O)O)(C(=O)CO)O)C(=C3C2=O)O)O |
| InChIKey | WAIUUSMYFGCHDB-WVHWHMGYSA-N |
Product Overview
7-O-Ribofuranosyladriamycinone (CAS 105445-03-2), with molecular formula C26H26O13 and molecular weight 546.14 g/mol. IUPAC: (7R,9S)-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione.
Chemical Property Profile of 7-O-Ribofuranosyladriamycinone
Property Insights of 7-O-Ribofuranosyladriamycinone
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 7-O-Ribofuranosyladriamycinone. The TPSA of 221.0 Ų indicates high polarity, suggesting 7-O-Ribofuranosyladriamycinone may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 7-O-Ribofuranosyladriamycinone has 7 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-O-Ribofuranosyladriamycinone?
The CAS number of 7-O-Ribofuranosyladriamycinone is 105445-03-2.
What is the molecular formula of 7-O-Ribofuranosyladriamycinone?
The molecular formula of 7-O-Ribofuranosyladriamycinone is C26H26O13.
What is the molecular weight of 7-O-Ribofuranosyladriamycinone?
The molecular weight of 7-O-Ribofuranosyladriamycinone is 546.14 g/mol.
Where can I buy 7-O-Ribofuranosyladriamycinone?
You can request a quote for 7-O-Ribofuranosyladriamycinone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-O-Ribofuranosyladriamycinone?
Yes, KEHONG BIO provides custom synthesis services for 7-O-Ribofuranosyladriamycinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.