6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione
TL;DR: 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione (CAS 105384-40-5) is a chemical compound with molecular formula C22H29FO4 and molecular weight 376.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,10R,13S,14S,16S,17R)-6-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: 6alpha-Fluoro-17,21-dihydroxy-16beta-methyl-pregna-4,9(11)-diene-3,20-dione, 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione, (6S,8S,10R,13S,14S,16S,17R)-6-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one, Pregna-4,9(11)-diene-3,20-dione, 6-fluoro-17,21-dihydroxy-16-methyl-, (6alpha,16beta)-, 6alpha-Fluoro-17,21-dihydroxy-16beta-methyl-pregna-4,9-(11)- diene-3,20-dione
| Molecular Formula | C22H29FO4 |
|---|---|
| Molecular Weight | 376.20 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.205 |
| Heavy Atoms | 27 |
| Complexity | 770.0 |
Chemical Identifiers
| CAS Number | 105384-40-5 |
|---|---|
| SMILES | C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)CC[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CO)O)C)C)F |
| InChIKey | MUEOUHRWNRABSW-LCMQHTLGSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione (CAS 105384-40-5), with molecular formula C22H29FO4 and molecular weight 376.20 g/mol. IUPAC: (6S,8S,10R,13S,14S,16S,17R)-6-fluoro-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione
Property Insights of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione. Following Lipinski's Rule of Five, 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione?
The CAS number of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione is 105384-40-5.
What is the molecular formula of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione?
The molecular formula of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione is C22H29FO4.
What is the molecular weight of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione?
The molecular weight of 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione is 376.20 g/mol.
Where can I buy 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione?
You can request a quote for 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione?
Yes, KEHONG BIO provides custom synthesis services for 6-Fluoro-17,21-dihydroxy-16-methylpregna-4,9(11)-diene-3,20-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.