5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one
TL;DR: 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one (CAS 105316-99-2) is a chemical compound with molecular formula C11H9N3OS and molecular weight 231.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(2-amino-1,3-thiazol-4-yl)-1,3-dihydroindol-2-one
Also Known As: 5-(2-Aminothiazol-4-yl)indolin-2-one, 5-(2-Aminothiazol-4-yl)Oxindole, 5-(2-amino-1,3-thiazol-4-yl)-1,3-dihydro-2H-indol-2-one, 5-(2-amino-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol-2-one, 2H-Indol-2-one, 5-(2-amino-4-thiazolyl)-1,3-dihydro-
| Molecular Formula | C11H9N3OS |
|---|---|
| Molecular Weight | 231.05 g/mol |
| LogP | 1.8869 |
| Topological Polar Surface Area | 68.01 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 231.04663 |
| Heavy Atoms | 16 |
| Complexity | 576.3587 |
Chemical Identifiers
| CAS Number | 105316-99-2 |
|---|---|
| SMILES | C1C2=C(C=CC(=C2)C3=CSC(=N3)N)NC1=O |
Product Overview
5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one (CAS 105316-99-2), with molecular formula C11H9N3OS and molecular weight 231.05 g/mol. IUPAC: 5-(2-amino-1,3-thiazol-4-yl)-1,3-dihydroindol-2-one.
Chemical Property Profile of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one
Property Insights of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one
The XLogP value of 1.8869 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one. The TPSA of 68.01 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one. Following Lipinski's Rule of Five, 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one?
The CAS number of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one is 105316-99-2.
What is the molecular formula of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one?
The molecular formula of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one is C11H9N3OS.
What is the molecular weight of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one?
The molecular weight of 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one is 231.05 g/mol.
Where can I buy 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one?
You can request a quote for 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(2-Amino-4-thiazolyl)-1,3-dihydro-2H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.