1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine
TL;DR: 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine (CAS 105281-07-0) is a chemical compound with molecular formula C9H12FN3O3 and molecular weight 229.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one
Also Known As: 5'-deoxy-FAC, 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine, 1-(2,5-Dideoxy-2-fluoro-.beta.-D-arabinofuranosyl)cytosine, 4-Amino-1-(2,5-dideoxy-2-fluoro-beta-D-arabinofuranosyl)pyrimidin-2(1H)-one, 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one
| Molecular Formula | C9H12FN3O3 |
|---|---|
| Molecular Weight | 229.09 g/mol |
| LogP | -0.2 |
| Topological Polar Surface Area | 88.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 229.08627 |
| Heavy Atoms | 16 |
| Complexity | 371.0 |
Chemical Identifiers
| CAS Number | 105281-07-0 |
|---|---|
| SMILES | C[C@@H]1[C@H]([C@@H]([C@@H](O1)N2C=CC(=NC2=O)N)F)O |
| InChIKey | OCXOUAZGYAUARN-PXBUCIJWSA-N |
Product Overview
1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine (CAS 105281-07-0), with molecular formula C9H12FN3O3 and molecular weight 229.09 g/mol. IUPAC: 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-methyloxolan-2-yl]pyrimidin-2-one.
Chemical Property Profile of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine
Property Insights of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine
The XLogP value of -0.2 indicates that 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 88.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine. Following Lipinski's Rule of Five, 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine?
The CAS number of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine is 105281-07-0.
What is the molecular formula of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine?
The molecular formula of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine is C9H12FN3O3.
What is the molecular weight of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine?
The molecular weight of 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine is 229.09 g/mol.
Where can I buy 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine?
You can request a quote for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine?
Yes, KEHONG BIO provides custom synthesis services for 1-(2,5-Dideoxy-2-fluoro-beta-D-arabinofuranosyl)cytosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.