RefChem:385470
TL;DR: RefChem:385470 (CAS 105271-29-2) is a chemical compound with molecular formula C24H22N4O3S and molecular weight 446.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methoxyphenyl)thiourea
Also Known As: N-(3-Methoxy-4-(2-methyl-4-oxo-3(4H)-quinazolinyl)phenyl)-N'-(4-methoxyphenyl)thiourea, Thiourea, N-(3-methoxy-4-(2-methyl-4-oxo-3(4H)-quinazolinyl)phenyl)-N'-(4-methoxyphenyl)-, 1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methoxyphenyl)thiourea, N'-[3-Methoxy-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl]-N-(4-methoxyphenyl)carbamimidothioic acid, RefChem:385470
| Molecular Formula | C24H22N4O3S |
|---|---|
| Molecular Weight | 446.14 g/mol |
| LogP | 4.52022 |
| Topological Polar Surface Area | 77.41 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 446.14127 |
| Heavy Atoms | 32 |
| Complexity | 1349.9572 |
Chemical Identifiers
| CAS Number | 105271-29-2 |
|---|---|
| SMILES | CC1=NC2=CC=CC=C2C(=O)N1C3=C(C=C(C=C3)NC(=S)NC4=CC=C(C=C4)OC)OC |
Product Overview
RefChem:385470 (CAS 105271-29-2), with molecular formula C24H22N4O3S and molecular weight 446.14 g/mol. IUPAC: 1-[3-methoxy-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]-3-(4-methoxyphenyl)thiourea.
Chemical Property Profile of RefChem:385470
Property Insights of RefChem:385470
The XLogP value of 4.52022 indicates that RefChem:385470 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.41 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:385470. Following Lipinski's Rule of Five, RefChem:385470 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:385470?
The CAS number of RefChem:385470 is 105271-29-2.
What is the molecular formula of RefChem:385470?
The molecular formula of RefChem:385470 is C24H22N4O3S.
What is the molecular weight of RefChem:385470?
The molecular weight of RefChem:385470 is 446.14 g/mol.
Where can I buy RefChem:385470?
You can request a quote for RefChem:385470 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:385470?
Yes, KEHONG BIO provides custom synthesis services for RefChem:385470 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.