2-Hydroxy-5-(trifluoromethyl)pyridine
TL;DR: 2-Hydroxy-5-(trifluoromethyl)pyridine (CAS 105047-45-8) is a chemical compound with molecular formula C6H4F3NO and molecular weight 163.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(trifluoromethyl)-1H-pyridin-2-one
Also Known As: 2-Hydroxy-5-(trifluoromethyl)pyridine, 5-(trifluoromethyl)pyridin-2-ol, 2-Hydroxy-5-trifluoromethylpyridine, Maybridge1_006426, 5-(Trifluoromethyl)-2-pyridinol
| Molecular Formula | C6H4F3NO |
|---|---|
| Molecular Weight | 163.02 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 0 |
| Exact Mass | 163.0245 |
| Heavy Atoms | 11 |
| Complexity | 239.0 |
Chemical Identifiers
| CAS Number | 105047-45-8 |
|---|---|
| SMILES | C1=CC(=O)NC=C1C(F)(F)F |
| InChIKey | BYRJSCNPUHYZQE-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 7 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-Hydroxy-5-(trifluoromethyl)pyridine (CAS 105047-45-8), with molecular formula C6H4F3NO and molecular weight 163.02 g/mol. IUPAC: 5-(trifluoromethyl)-1H-pyridin-2-one.
Chemical Property Profile of 2-Hydroxy-5-(trifluoromethyl)pyridine
Property Insights of 2-Hydroxy-5-(trifluoromethyl)pyridine
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Hydroxy-5-(trifluoromethyl)pyridine. With a topological polar surface area (TPSA) of 29.1 Ų, 2-Hydroxy-5-(trifluoromethyl)pyridine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Hydroxy-5-(trifluoromethyl)pyridine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Hydroxy-5-(trifluoromethyl)pyridine?
The CAS number of 2-Hydroxy-5-(trifluoromethyl)pyridine is 105047-45-8.
What is the molecular formula of 2-Hydroxy-5-(trifluoromethyl)pyridine?
The molecular formula of 2-Hydroxy-5-(trifluoromethyl)pyridine is C6H4F3NO.
What is the molecular weight of 2-Hydroxy-5-(trifluoromethyl)pyridine?
The molecular weight of 2-Hydroxy-5-(trifluoromethyl)pyridine is 163.02 g/mol.
Where can I buy 2-Hydroxy-5-(trifluoromethyl)pyridine?
You can request a quote for 2-Hydroxy-5-(trifluoromethyl)pyridine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Hydroxy-5-(trifluoromethyl)pyridine?
Yes, KEHONG BIO provides custom synthesis services for 2-Hydroxy-5-(trifluoromethyl)pyridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.