3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine structure

3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine

TL;DR: 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine (CAS 104987-44-2) is a chemical compound with molecular formula C22H26F3N3O7 and molecular weight 501.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(2R,3S)-2-(2,2-dimethylpropanoyloxymethyl)-5-[2,4-dioxo-5-(trifluoromethyl)pyrimidin-1-yl]oxolan-3-yl] 1-methyl-4H-pyridine-3-carboxylate

Also Known As: DHTFT, 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine, [(2R,3S)-2-(2,2-dimethylpropanoyloxymethyl)-5-[2,4-dioxo-5-(trifluoromethyl)pyrimidin-1-yl]oxolan-3-yl] 1-methyl-4H-pyridine-3-carboxylate, 3/'-(N-methyl-1,4-nicotinoyl)-5/'-pivaloyltrifluorothymidine, 3'-(N-methyl-1,4-dihydronicotinoyl)-5'-pivaloyltrifluorothymidine

CAS: 104987-44-2
Molecular Formula C22H26F3N3O7
Molecular Weight 501.17 g/mol
LogP 2.4
Topological Polar Surface Area 114.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 11
Rotatable Bonds 8
Exact Mass 501.17227
Heavy Atoms 35
Complexity 997.0

Chemical Identifiers

CAS Number 104987-44-2
SMILES CC(C)(C)C(=O)OC[C@@H]1[C@H](CC(O1)N2C=C(C(=O)NC2=O)C(F)(F)F)OC(=O)C3=CN(C=CC3)C
InChIKey PUUXKDCZTQOAGJ-QMRHZFGWSA-N

Product Overview

3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine (CAS 104987-44-2), with molecular formula C22H26F3N3O7 and molecular weight 501.17 g/mol. IUPAC: [(2R,3S)-2-(2,2-dimethylpropanoyloxymethyl)-5-[2,4-dioxo-5-(trifluoromethyl)pyrimidin-1-yl]oxolan-3-yl] 1-methyl-4H-pyridine-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine

XLogP
2.4
TPSA (Topological Polar Surface Area)
114.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
11
Rotatable Bonds
8
Heavy Atoms
35
Complexity
997.0
Exact Mass
501.17227
Monoisotopic Mass
501.17227
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine

The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine. Following Lipinski's Rule of Five, 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine has 1 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine?

The CAS number of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine is 104987-44-2.

What is the molecular formula of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine?

The molecular formula of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine is C22H26F3N3O7.

What is the molecular weight of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine?

The molecular weight of 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine is 501.17 g/mol.

Where can I buy 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine?

You can request a quote for 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine?

Yes, KEHONG BIO provides custom synthesis services for 3'-(N-methyl-1,4-nicotinoyl)-5'-pivaloyltrifluorothymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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