Difril structure

Difril

TL;DR: Difril (CAS 1049-27-0) is a chemical compound with molecular formula C24H28ClN and molecular weight 365.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

Difril

3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine;hydrochloride

Also Known As: Difril, Corontin, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamine hydrochloride, 3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine;hydrochloride, N-(1-Methyl-2-phenylethyl)-gamma-phenylbenzenepropanamine hydrochloride

CAS: 1049-27-0
Molecular Formula C24H28ClN
Molecular Weight 365.19 g/mol
LogP 5.85
Topological Polar Surface Area 12.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 1
Rotatable Bonds 8
Exact Mass 365.19104
Heavy Atoms 26
Complexity 316.0

Chemical Identifiers

CAS Number 1049-27-0
SMILES CC(CC1=CC=CC=C1)NCCC(C2=CC=CC=C2)C3=CC=CC=C3.Cl
InChIKey MZICOCXOCXGTEM-UHFFFAOYSA-N

Product Overview

Difril (CAS 1049-27-0), with molecular formula C24H28ClN and molecular weight 365.19 g/mol. IUPAC: 3,3-diphenyl-N-(1-phenylpropan-2-yl)propan-1-amine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Difril

XLogP
5.85
TPSA (Topological Polar Surface Area)
12.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
1
Rotatable Bonds
8
Heavy Atoms
26
Complexity
316.0
Exact Mass
365.19104
Monoisotopic Mass
365.19104
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Difril

The XLogP value of 5.85 indicates that Difril is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, Difril exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Difril has 2 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Difril?

The CAS number of Difril is 1049-27-0.

What is the molecular formula of Difril?

The molecular formula of Difril is C24H28ClN.

What is the molecular weight of Difril?

The molecular weight of Difril is 365.19 g/mol.

Where can I buy Difril?

You can request a quote for Difril directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Difril?

Yes, KEHONG BIO provides custom synthesis services for Difril and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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