Ro 19-8022
TL;DR: Ro 19-8022 (CAS 104604-66-2) is a chemical compound with molecular formula C25H21ClN2O3 and molecular weight 432.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-chloro-1-[(2R)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-3-phenylbenzo[a]quinolizin-4-one
Also Known As: Ro 19-8022, Ro-19-8022, ro19-8022, SID:134224084, (R)-1-((10-Chloro-4-oxo-3-phenyl-4H-benzo(a)quinolizin-1-yl)carbonyl)-2-pyrrolidinemethanol
| Molecular Formula | C25H21ClN2O3 |
|---|---|
| Molecular Weight | 432.12 g/mol |
| LogP | 4.37 |
| Topological Polar Surface Area | 62.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 432.12408 |
| Heavy Atoms | 31 |
| Complexity | 1364.3235 |
Chemical Identifiers
| CAS Number | 104604-66-2 |
|---|---|
| SMILES | C1C[C@@H](N(C1)C(=O)C2=C3C4=C(C=CC(=C4)Cl)C=CN3C(=O)C(=C2)C5=CC=CC=C5)CO |
Product Overview
Ro 19-8022 (CAS 104604-66-2), with molecular formula C25H21ClN2O3 and molecular weight 432.12 g/mol. IUPAC: 10-chloro-1-[(2R)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-3-phenylbenzo[a]quinolizin-4-one.
Chemical Property Profile of Ro 19-8022
Property Insights of Ro 19-8022
The XLogP value of 4.37 indicates that Ro 19-8022 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.02 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 19-8022. Following Lipinski's Rule of Five, Ro 19-8022 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ro 19-8022?
The CAS number of Ro 19-8022 is 104604-66-2.
What is the molecular formula of Ro 19-8022?
The molecular formula of Ro 19-8022 is C25H21ClN2O3.
What is the molecular weight of Ro 19-8022?
The molecular weight of Ro 19-8022 is 432.12 g/mol.
Where can I buy Ro 19-8022?
You can request a quote for Ro 19-8022 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ro 19-8022?
Yes, KEHONG BIO provides custom synthesis services for Ro 19-8022 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.