Ro 195686 structure

Ro 195686

TL;DR: Ro 195686 (CAS 104604-60-6) is a chemical compound with molecular formula C24H22N2O3S and molecular weight 418.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

10-[(2R)-2-(methoxymethyl)pyrrolidine-1-carbonyl]-8-phenylthieno[2,3-a]quinolizin-7-one

Also Known As: MOTQP, Ro 195686, Ro 19-5686, Ro-19-5686, 2-(Methoxymethyl)-1-((7-oxo-8-phenyl-7H-thieno(2,3-a)quinolizin-10-yl)carbonyl)pyrrolidine

CAS: 104604-60-6
Molecular Formula C24H22N2O3S
Molecular Weight 418.14 g/mol
LogP 3.1
Topological Polar Surface Area 78.1 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 418.1351
Heavy Atoms 30
Complexity 811.0

Chemical Identifiers

CAS Number 104604-60-6
SMILES COC[C@H]1CCCN1C(=O)C2=C3C4=C(C=CN3C(=O)C(=C2)C5=CC=CC=C5)C=CS4
InChIKey FPZGMBQNUCUBND-GOSISDBHSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (18 patents) Pharmaceutical Intermediates (16 patents)

Product Overview

Ro 195686 (CAS 104604-60-6), with molecular formula C24H22N2O3S and molecular weight 418.14 g/mol. IUPAC: 10-[(2R)-2-(methoxymethyl)pyrrolidine-1-carbonyl]-8-phenylthieno[2,3-a]quinolizin-7-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Ro 195686

XLogP
3.1
TPSA (Topological Polar Surface Area)
78.1
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
30
Complexity
811.0
Exact Mass
418.1351
Monoisotopic Mass
418.1351
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ro 195686

The XLogP value of 3.1 indicates that Ro 195686 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Ro 195686. Following Lipinski's Rule of Five, Ro 195686 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ro 195686?

The CAS number of Ro 195686 is 104604-60-6.

What is the molecular formula of Ro 195686?

The molecular formula of Ro 195686 is C24H22N2O3S.

What is the molecular weight of Ro 195686?

The molecular weight of Ro 195686 is 418.14 g/mol.

Where can I buy Ro 195686?

You can request a quote for Ro 195686 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ro 195686?

Yes, KEHONG BIO provides custom synthesis services for Ro 195686 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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