HOTQP
TL;DR: HOTQP (CAS 104604-59-3) is a chemical compound with molecular formula C23H20N2O3S and molecular weight 404.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-[(2R)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-8-phenylthieno[2,3-a]quinolizin-7-one
Also Known As: HOTQP, 1-dimethylamino-2-pentyn-5-ol, Ro-19-5663, 2-(Hydroxymethyl)-1-((7-oxo-8-phenyl-7H-thieno(2,3-a)quinolizin-10-yl)carbonyl)pyrrolidine, 10-[(2R)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-8-phenylthieno[2,3-a]quinolizin-7-one
| Molecular Formula | C23H20N2O3S |
|---|---|
| Molecular Weight | 404.12 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 89.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 404.11948 |
| Heavy Atoms | 29 |
| Complexity | 796.0 |
Chemical Identifiers
| CAS Number | 104604-59-3 |
|---|---|
| SMILES | C1C[C@@H](N(C1)C(=O)C2=C3C4=C(C=CN3C(=O)C(=C2)C5=CC=CC=C5)C=CS4)CO |
| InChIKey | UBUSBVSRCKDQNL-QGZVFWFLSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
HOTQP (CAS 104604-59-3), with molecular formula C23H20N2O3S and molecular weight 404.12 g/mol. IUPAC: 10-[(2R)-2-(hydroxymethyl)pyrrolidine-1-carbonyl]-8-phenylthieno[2,3-a]quinolizin-7-one.
Chemical Property Profile of HOTQP
Property Insights of HOTQP
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for HOTQP. The TPSA of 89.1 Ų falls within the moderate polarity range, balancing permeability and solubility for HOTQP. Following Lipinski's Rule of Five, HOTQP has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of HOTQP?
The CAS number of HOTQP is 104604-59-3.
What is the molecular formula of HOTQP?
The molecular formula of HOTQP is C23H20N2O3S.
What is the molecular weight of HOTQP?
The molecular weight of HOTQP is 404.12 g/mol.
Where can I buy HOTQP?
You can request a quote for HOTQP directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for HOTQP?
Yes, KEHONG BIO provides custom synthesis services for HOTQP and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.