![5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine structure](/static/products/104/10445-04-2.png)
5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine
TL;DR: 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine (CAS 10445-04-2) is a chemical compound with molecular formula C9H6F3N3S and molecular weight 245.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[4-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine
Also Known As: 5-[4-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine, 5-(4-(Trifluoromethyl)phenyl)-1,3,4-thiadiazol-2-amine, 5-(4-trifluoromethyl-phenyl)-[1,3,4]thiadiazol-2-ylamine, 5-(4-Trifluormethyl-phenyl)-2-amino-1,3,4-thiadiazol, 5-4-(Trifluoromethyl)phenyl-1,3,4-thiadiazol-2-amine
| Molecular Formula | C9H6F3N3S |
|---|---|
| Molecular Weight | 245.02 g/mol |
| LogP | 2.8061 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 245.02345 |
| Heavy Atoms | 16 |
| Complexity | 489.44547 |
Chemical Identifiers
| CAS Number | 10445-04-2 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NN=C(S2)N)C(F)(F)F |
Product Overview
5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine (CAS 10445-04-2), with molecular formula C9H6F3N3S and molecular weight 245.02 g/mol. IUPAC: 5-[4-(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine.
Chemical Property Profile of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine
Property Insights of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine
The XLogP value of 2.8061 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine. With a topological polar surface area (TPSA) of 51.8 Ų, 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine?
The CAS number of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine is 10445-04-2.
What is the molecular formula of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine?
The molecular formula of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine is C9H6F3N3S.
What is the molecular weight of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine?
The molecular weight of 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine is 245.02 g/mol.
Where can I buy 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine?
You can request a quote for 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-[4-(Trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.