4-Chlorophenyl Isocyanate structure

4-Chlorophenyl Isocyanate

TL;DR: 4-Chlorophenyl Isocyanate (CAS 104-12-1) is a chemical compound with molecular formula C7H4ClNO and molecular weight 153.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-chloro-4-isocyanatobenzene

Also Known As: 4-Chlorophenyl isocyanate, 1-Chloro-4-isocyanatobenzene, p-Chlorophenyl isocyanate, PCPI, 4-Chloroisocyanatobenzene

CAS: 104-12-1
Molecular Formula C7H4ClNO
Molecular Weight 153.00 g/mol
LogP 3.3
Topological Polar Surface Area 29.4 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 152.99814
Heavy Atoms 10
Complexity 146.0
Melting Point 31.3 °C
Boiling Point 204 °C
Density Density: 1.25 g/cu cm at 40 °C
Solubility Soluble in organic solvents
Flash Point 110 °C
Vapor Pressure 95.4 [mmHg]
Refractive Index 1.5543 at 40 °C

Chemical Identifiers

CAS Number 104-12-1
SMILES C1=CC(=CC=C1N=C=O)Cl
InChIKey ADAKRBAJFHTIEW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 22 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (261 patents) Analytical Reagents (18 patents) Biotechnology (10 patents) Catalysts (15 patents) Coatings & Adhesives (64 patents) +17 more

Product Overview

4-Chlorophenyl Isocyanate (CAS 104-12-1), with molecular formula C7H4ClNO and molecular weight 153.00 g/mol. IUPAC: 1-chloro-4-isocyanatobenzene.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Chlorophenyl Isocyanate

XLogP
3.3
TPSA (Topological Polar Surface Area)
29.4
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
10
Complexity
146.0
Exact Mass
152.99814
Monoisotopic Mass
152.99814
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Chlorophenyl Isocyanate

The XLogP value of 3.3 indicates that 4-Chlorophenyl Isocyanate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.4 Ų, 4-Chlorophenyl Isocyanate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chlorophenyl Isocyanate has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Chlorophenyl Isocyanate?

The CAS number of 4-Chlorophenyl Isocyanate is 104-12-1.

What is the molecular formula of 4-Chlorophenyl Isocyanate?

The molecular formula of 4-Chlorophenyl Isocyanate is C7H4ClNO.

What is the molecular weight of 4-Chlorophenyl Isocyanate?

The molecular weight of 4-Chlorophenyl Isocyanate is 153.00 g/mol.

Where can I buy 4-Chlorophenyl Isocyanate?

You can request a quote for 4-Chlorophenyl Isocyanate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Chlorophenyl Isocyanate?

Yes, KEHONG BIO provides custom synthesis services for 4-Chlorophenyl Isocyanate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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