Cox-2-IN-18 structure

Cox-2-IN-18

TL;DR: Cox-2-IN-18 (CAS 1038061-96-9) is a chemical compound with molecular formula C18H19N3O3S2 and molecular weight 389.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-[2-(2-ethylsulfanyl-4-oxoquinazolin-3-yl)ethyl]benzenesulfonamide

Also Known As: COX-2-IN-18, 4-[2-(2-ethylsulfanyl-4-oxoquinazolin-3-yl)ethyl]benzenesulfonamide

CAS: 1038061-96-9
Molecular Formula C18H19N3O3S2
Molecular Weight 389.09 g/mol
LogP 2.3986
Topological Polar Surface Area 95.05 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 6
Exact Mass 389.0868
Heavy Atoms 26
Complexity 1090.8596

Chemical Identifiers

CAS Number 1038061-96-9
SMILES CCSC1=NC2=CC=CC=C2C(=O)N1CCC3=CC=C(C=C3)S(=O)(=O)N

Product Overview

Cox-2-IN-18 (CAS 1038061-96-9), with molecular formula C18H19N3O3S2 and molecular weight 389.09 g/mol. IUPAC: 4-[2-(2-ethylsulfanyl-4-oxoquinazolin-3-yl)ethyl]benzenesulfonamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Cox-2-IN-18

XLogP
2.3986
TPSA (Topological Polar Surface Area)
95.05
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
6
Heavy Atoms
26
Complexity
1090.8596
Exact Mass
389.0868
Monoisotopic Mass
389.0868
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Cox-2-IN-18

The XLogP value of 2.3986 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Cox-2-IN-18. The TPSA of 95.05 Ų falls within the moderate polarity range, balancing permeability and solubility for Cox-2-IN-18. Following Lipinski's Rule of Five, Cox-2-IN-18 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Cox-2-IN-18?

The CAS number of Cox-2-IN-18 is 1038061-96-9.

What is the molecular formula of Cox-2-IN-18?

The molecular formula of Cox-2-IN-18 is C18H19N3O3S2.

What is the molecular weight of Cox-2-IN-18?

The molecular weight of Cox-2-IN-18 is 389.09 g/mol.

Where can I buy Cox-2-IN-18?

You can request a quote for Cox-2-IN-18 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Cox-2-IN-18?

Yes, KEHONG BIO provides custom synthesis services for Cox-2-IN-18 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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