Colchiceine analog
TL;DR: Colchiceine analog (CAS 102491-70-3) is a chemical compound with molecular formula C21H20F3NO6 and molecular weight 439.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-N-[(7S)-10-hydroxy-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Colchiceine analog, N-Trifluoroacetyl Deacetylcolchiceine, TimTec1_005126, N-Trifluoroacetyl-N-deacetylcolchiceine, (R/S)-N-Deacetyl Colchiceine N-Trifluroracetate
| Molecular Formula | C21H20F3NO6 |
|---|---|
| Molecular Weight | 439.12 g/mol |
| LogP | 1.8 |
| Topological Polar Surface Area | 94.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 439.12427 |
| Heavy Atoms | 31 |
| Complexity | 818.0 |
Chemical Identifiers
| CAS Number | 102491-70-3 |
|---|---|
| SMILES | COC1=C(C(=C2C(=C1)CC[C@@H](C3=CC(=O)C(=CC=C32)O)NC(=O)C(F)(F)F)OC)OC |
| InChIKey | GZXFPMJSKAABTM-ZDUSSCGKSA-N |
Product Overview
Colchiceine analog (CAS 102491-70-3), with molecular formula C21H20F3NO6 and molecular weight 439.12 g/mol. IUPAC: 2,2,2-trifluoro-N-[(7S)-10-hydroxy-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Colchiceine analog
Property Insights of Colchiceine analog
The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Colchiceine analog. The TPSA of 94.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchiceine analog. Following Lipinski's Rule of Five, Colchiceine analog has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchiceine analog?
The CAS number of Colchiceine analog is 102491-70-3.
What is the molecular formula of Colchiceine analog?
The molecular formula of Colchiceine analog is C21H20F3NO6.
What is the molecular weight of Colchiceine analog?
The molecular weight of Colchiceine analog is 439.12 g/mol.
Where can I buy Colchiceine analog?
You can request a quote for Colchiceine analog directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchiceine analog?
Yes, KEHONG BIO provides custom synthesis services for Colchiceine analog and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.