![1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine structure](/static/products/1024/1024338-68-8.webp)
1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine
TL;DR: 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine (CAS 1024338-68-8) is a chemical compound with molecular formula C16H15ClF3N3OS and molecular weight 389.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-(3-methylthiophen-2-yl)methanone
Also Known As: 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine, [4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-(3-methylthiophen-2-yl)methanone, 4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL 3-METHYL(2-THIENYL) KETONE, (4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(3-methylthiophen-2-yl)methanone, [4-[3-chloro-5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]-(3-methyl-2-thienyl)methanone
| Molecular Formula | C16H15ClF3N3OS |
|---|---|
| Molecular Weight | 389.06 g/mol |
| LogP | 4.08612 |
| Topological Polar Surface Area | 36.44 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 389.05765 |
| Heavy Atoms | 25 |
| Complexity | 785.1724 |
Chemical Identifiers
| CAS Number | 1024338-68-8 |
|---|---|
| SMILES | CC1=C(SC=C1)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)Cl |
Product Overview
1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine (CAS 1024338-68-8), with molecular formula C16H15ClF3N3OS and molecular weight 389.06 g/mol. IUPAC: [4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-(3-methylthiophen-2-yl)methanone.
Chemical Property Profile of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine
Property Insights of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine
The XLogP value of 4.08612 indicates that 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.44 Ų, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine?
The CAS number of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine is 1024338-68-8.
What is the molecular formula of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine?
The molecular formula of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine is C16H15ClF3N3OS.
What is the molecular weight of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine?
The molecular weight of 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine is 389.06 g/mol.
Where can I buy 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine?
You can request a quote for 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-4-(3-methylthiophene-2-carbonyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.