8R-0369 structure

8R-0369

TL;DR: 8R-0369 (CAS 1024017-29-5) is a chemical compound with molecular formula C26H28FN3O3S and molecular weight 481.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(cyclohexylmethyl)-5-[(4-fluorophenyl)methylsulfanyl]-8,9-dimethoxy-3H-imidazo[1,2-c]quinazolin-2-one

Also Known As: 8R-0369, 3-(cyclohexylmethyl)-5-[(4-fluorobenzyl)sulfanyl]-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one, 3-(cyclohexylmethyl)-5-[(4-fluorophenyl)methylsulfanyl]-8,9-dimethoxy-3H-imidazo[1,2-c]quinazolin-2-one, 3-(cyclohexylmethyl)-5-{[(4-fluorophenyl)methyl]sulfanyl}-8,9-dimethoxy-2H,3H-imidazo[1,2-c]quinazolin-2-one

CAS: 1024017-29-5
Molecular Formula C26H28FN3O3S
Molecular Weight 481.18 g/mol
LogP 5.7052
Topological Polar Surface Area 63.49 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 481.18353
Heavy Atoms 34
Complexity 1142.725

Chemical Identifiers

CAS Number 1024017-29-5
SMILES COC1=C(C=C2C(=C1)C3=NC(=O)C(N3C(=N2)SCC4=CC=C(C=C4)F)CC5CCCCC5)OC

Product Overview

8R-0369 (CAS 1024017-29-5), with molecular formula C26H28FN3O3S and molecular weight 481.18 g/mol. IUPAC: 3-(cyclohexylmethyl)-5-[(4-fluorophenyl)methylsulfanyl]-8,9-dimethoxy-3H-imidazo[1,2-c]quinazolin-2-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 8R-0369

XLogP
5.7052
TPSA (Topological Polar Surface Area)
63.49
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
34
Complexity
1142.725
Exact Mass
481.18353
Monoisotopic Mass
481.18353
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 8R-0369

The XLogP value of 5.7052 indicates that 8R-0369 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.49 Ų falls within the moderate polarity range, balancing permeability and solubility for 8R-0369. Following Lipinski's Rule of Five, 8R-0369 has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 8R-0369?

The CAS number of 8R-0369 is 1024017-29-5.

What is the molecular formula of 8R-0369?

The molecular formula of 8R-0369 is C26H28FN3O3S.

What is the molecular weight of 8R-0369?

The molecular weight of 8R-0369 is 481.18 g/mol.

Where can I buy 8R-0369?

You can request a quote for 8R-0369 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 8R-0369?

Yes, KEHONG BIO provides custom synthesis services for 8R-0369 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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