Lomerizine Hydrochloride
TL;DR: Lomerizine Hydrochloride (CAS 101477-54-7) is a chemical compound with molecular formula C27H32Cl2F2N2O3 and molecular weight 540.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
Also Known As: Lomerizine dihydrochloride, Lomerizine hydrochloride, lomerizine, Lomerizine HCl, Terranas
| Molecular Formula | C27H32Cl2F2N2O3 |
|---|---|
| Molecular Weight | 540.18 g/mol |
| LogP | 5.74 |
| Topological Polar Surface Area | 34.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 8 |
| Exact Mass | 540.1758 |
| Heavy Atoms | 36 |
| Complexity | 568.0 |
Chemical Identifiers
| CAS Number | 101477-54-7 |
|---|---|
| SMILES | COC1=C(C(=C(C=C1)CN2CCN(CC2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC)OC.Cl.Cl |
| InChIKey | LOGVKVSFYBBUAJ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Lomerizine Hydrochloride (CAS 101477-54-7), with molecular formula C27H32Cl2F2N2O3 and molecular weight 540.18 g/mol. IUPAC: 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride.
Chemical Property Profile of Lomerizine Hydrochloride
Property Insights of Lomerizine Hydrochloride
The XLogP value of 5.74 indicates that Lomerizine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.2 Ų, Lomerizine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Lomerizine Hydrochloride has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Lomerizine Hydrochloride?
The CAS number of Lomerizine Hydrochloride is 101477-54-7.
What is the molecular formula of Lomerizine Hydrochloride?
The molecular formula of Lomerizine Hydrochloride is C27H32Cl2F2N2O3.
What is the molecular weight of Lomerizine Hydrochloride?
The molecular weight of Lomerizine Hydrochloride is 540.18 g/mol.
Where can I buy Lomerizine Hydrochloride?
You can request a quote for Lomerizine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Lomerizine Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Lomerizine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.