![methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate structure](/static/products/101/1014089-10-1.png)
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate
概要：methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate（CAS 1014089-10-1）是一种化学化合物，分子式为C26H27N3O5S，分子量为493.17 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
methyl 2-[(3aR,4S,8aS,8bS)-1'-ethyl-1,2',3-trioxospiro[3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine-4,3'-indole]-2-yl]-4,5-dimethylthiophene-3-carboxylate
又称：methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate, methyl 2-[(3aR,4S,8aS,8bS)-1'-ethyl-1,2',3-trioxospiro[3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine-4,3'-indole]-2-yl]-4,5-dimethylthiophene-3-carboxylate
| 分子式 | C26H27N3O5S |
|---|---|
| 分子量 | 493.17 g/mol |
| LogP | 2.99714 |
| 拓扑极性表面积 | 87.23 Ų |
| 氢键供体数 | 0 |
| 氢键受体数 | 7 |
| 可旋转键数 | 3 |
| 精确质量 | 493.16714 |
| 重原子数 | 35 |
| 复杂度 | 1318.0508 |
化学标识符
| CAS 编号 | 1014089-10-1 |
|---|---|
| SMILES | CCN1C2=CC=CC=C2[C@]3(C1=O)[C@H]4[C@@H]([C@H]5N3CCC5)C(=O)N(C4=O)C6=C(C(=C(S6)C)C)C(=O)OC |
产品概述
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate（CAS 1014089-10-1），分子式为C26H27N3O5S，分子量为493.17 g/mol。IUPAC名：methyl 2-[(3aR,4S,8aS,8bS)-1'-ethyl-1,2',3-trioxospiro[3a,6,7,8,8a,8b-hexahydropyrrolo[3,4-a]pyrrolizine-4,3'-indole]-2-yl]-4,5-dimethylthiophene-3-carboxylate。
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate化学性质概览
属性洞察：methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的XLogP值为2.99714，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为87.23 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate有0个氢键供体和7个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的CAS号是多少？
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的CAS号为1014089-10-1。
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的分子式是什么？
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的分子式为C26H27N3O5S。
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的分子量是多少？
methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的分子量为493.17 g/mol。
在哪里可以购买methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate？
您可以直接向科弘生物询价methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate的定制合成服务？
是的，科弘生物提供methyl 2-((3S,3a'R,8a'S,8b'S)-1-ethyl-1',2,3'-trioxo-3',3a',6',7',8',8a'-hexahydro-1'H-spiro[indoline-3,4'-pyrrolo[3,4-a]pyrrolizine]-2'(8b'H)-yl)-4,5-dimethylthiophene-3-carboxylate及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。