3-(Trifluoromethoxy)benzoic acid structure

3-(Trifluoromethoxy)benzoic acid

TL;DR: 3-(Trifluoromethoxy)benzoic acid (CAS 1014-81-9) is a chemical compound with molecular formula C8H5F3O3 and molecular weight 206.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

3-(trifluoromethoxy)benzoic acid

Also Known As: 3-(Trifluoromethoxy)benzoic acid, Benzoic acid, 3-(trifluoromethoxy)-, m-Trifluoromethoxybenzoic acid, 3-trifluoromethoxybenzoic acid, m-(trifluoromethoxy)benzoic acid

CAS: 1014-81-9
Molecular Formula C8H5F3O3
Molecular Weight 206.02 g/mol
LogP 3.2
Topological Polar Surface Area 46.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 2
Exact Mass 206.01907
Heavy Atoms 14
Complexity 214.0

Chemical Identifiers

CAS Number 1014-81-9
SMILES C1=CC(=CC(=C1)OC(F)(F)F)C(=O)O
InChIKey OKPFIWIMBJNFSE-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (2 patents) Heterocyclic Building Blocks (164 patents) Lubricants & Additives (2 patents) Organic Building Blocks (44 patents) Pharmaceutical Intermediates (205 patents)

Product Overview

3-(Trifluoromethoxy)benzoic acid (CAS 1014-81-9), with molecular formula C8H5F3O3 and molecular weight 206.02 g/mol. IUPAC: 3-(trifluoromethoxy)benzoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 3-(Trifluoromethoxy)benzoic acid

XLogP
3.2
TPSA (Topological Polar Surface Area)
46.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
2
Heavy Atoms
14
Complexity
214.0
Exact Mass
206.01907
Monoisotopic Mass
206.01907
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-(Trifluoromethoxy)benzoic acid

The XLogP value of 3.2 indicates that 3-(Trifluoromethoxy)benzoic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.5 Ų, 3-(Trifluoromethoxy)benzoic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(Trifluoromethoxy)benzoic acid has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-(Trifluoromethoxy)benzoic acid?

The CAS number of 3-(Trifluoromethoxy)benzoic acid is 1014-81-9.

What is the molecular formula of 3-(Trifluoromethoxy)benzoic acid?

The molecular formula of 3-(Trifluoromethoxy)benzoic acid is C8H5F3O3.

What is the molecular weight of 3-(Trifluoromethoxy)benzoic acid?

The molecular weight of 3-(Trifluoromethoxy)benzoic acid is 206.02 g/mol.

Where can I buy 3-(Trifluoromethoxy)benzoic acid?

You can request a quote for 3-(Trifluoromethoxy)benzoic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-(Trifluoromethoxy)benzoic acid?

Yes, KEHONG BIO provides custom synthesis services for 3-(Trifluoromethoxy)benzoic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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