KW-2170 free base
TL;DR: KW-2170 free base (CAS 101321-16-8) is a chemical compound with molecular formula C20H23N5O4 and molecular weight 397.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
10-(3-aminopropylamino)-3,8-dihydroxy-14-[(2-hydroxyethylamino)methyl]-1,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,7,9,11,13(16),14-heptaen-6-one
Also Known As: KW-2170 free base, Kw 2170, J1.156.172A, 6H-Pyrazolo(4,5,1-de)acridin-6-one, 5-((3-aminopropyl)amino)-7,10-dihydroxy-2-(((2-hydroxyethyl)amino)methyl)-, 10-[(3-aminopropyl)amino]-3,6-dihydroxy-14-{[(2-hydroxyethyl)amino]methyl}-1,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,6,9(16),10,12,14-heptaen-8-one
| Molecular Formula | C20H23N5O4 |
|---|---|
| Molecular Weight | 397.18 g/mol |
| LogP | 0.6925 |
| Topological Polar Surface Area | 145.14 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 397.17502 |
| Heavy Atoms | 29 |
| Complexity | 1237.0747 |
Chemical Identifiers
| CAS Number | 101321-16-8 |
|---|---|
| SMILES | C1=CC(=C2C3=C1C(=NN3C4=C(C=CC(=O)C4=C2O)O)CNCCO)NCCCN |
Product Overview
KW-2170 free base (CAS 101321-16-8), with molecular formula C20H23N5O4 and molecular weight 397.18 g/mol. IUPAC: 10-(3-aminopropylamino)-3,8-dihydroxy-14-[(2-hydroxyethylamino)methyl]-1,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-2,4,7,9,11,13(16),14-heptaen-6-one.
Chemical Property Profile of KW-2170 free base
Property Insights of KW-2170 free base
The XLogP value of 0.6925 suggests moderate lipophilicity, balancing water solubility and membrane permeability for KW-2170 free base. The TPSA of 145.14 Ų indicates high polarity, suggesting KW-2170 free base may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, KW-2170 free base has 6 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of KW-2170 free base?
The CAS number of KW-2170 free base is 101321-16-8.
What is the molecular formula of KW-2170 free base?
The molecular formula of KW-2170 free base is C20H23N5O4.
What is the molecular weight of KW-2170 free base?
The molecular weight of KW-2170 free base is 397.18 g/mol.
Where can I buy KW-2170 free base?
You can request a quote for KW-2170 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for KW-2170 free base?
Yes, KEHONG BIO provides custom synthesis services for KW-2170 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.