![(5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one structure](/static/products/101/1010868-29-7.png)
(5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
TL;DR: (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one (CAS 1010868-29-7) is a chemical compound with molecular formula C26H16FN5O2S and molecular weight 481.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
Also Known As: (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one, (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-{[3-(furan-2-yl)-1-phenyl-1H-pyrazol-4-yl]methylidene}[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one, (Z)-2-((E)-4-fluorostyryl)-5-((3-(furan-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
| Molecular Formula | C26H16FN5O2S |
|---|---|
| Molecular Weight | 481.10 g/mol |
| LogP | 4.4539 |
| Topological Polar Surface Area | 78.22 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 481.10086 |
| Heavy Atoms | 35 |
| Complexity | 1765.4255 |
Chemical Identifiers
| CAS Number | 1010868-29-7 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C=C(C(=N2)C3=CC=CO3)/C=C\4/C(=O)N5C(=NC(=N5)/C=C/C6=CC=C(C=C6)F)S4 |
Product Overview
(5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one (CAS 1010868-29-7), with molecular formula C26H16FN5O2S and molecular weight 481.10 g/mol. IUPAC: (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one.
Chemical Property Profile of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
Property Insights of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
The XLogP value of 4.4539 indicates that (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.22 Ų falls within the moderate polarity range, balancing permeability and solubility for (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one. Following Lipinski's Rule of Five, (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one?
The CAS number of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one is 1010868-29-7.
What is the molecular formula of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one?
The molecular formula of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one is C26H16FN5O2S.
What is the molecular weight of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one?
The molecular weight of (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one is 481.10 g/mol.
Where can I buy (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one?
You can request a quote for (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-2-[(E)-2-(4-fluorophenyl)ethenyl]-5-[[3-(furan-2-yl)-1-phenylpyrazol-4-yl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.