N-(5-chloro-2-pyridinyl)-3-phenylacrylamide
TL;DR: N-(5-chloro-2-pyridinyl)-3-phenylacrylamide (CAS 100622-76-2) is a chemical compound with molecular formula C14H11ClN2O and molecular weight 258.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(5-chloro-2-pyridinyl)-3-phenylprop-2-enamide
Also Known As: N-(5-chloro-2-pyridinyl)-3-phenylacrylamide, N-(5-chloropyridin-2-yl)cinnamamide, (E)-N-(5-chloropyridin-2-yl)-3-phenylprop-2-enamide, (2E)-N-(5-chloropyridin-2-yl)-3-phenylprop-2-enamide, (E)-N-(5-chloro-2-pyridyl)-3-phenyl-acrylamide
| Molecular Formula | C14H11ClN2O |
|---|---|
| Molecular Weight | 258.06 g/mol |
| LogP | 3.1 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 258.056 |
| Heavy Atoms | 18 |
| Complexity | 300.0 |
Chemical Identifiers
| CAS Number | 100622-76-2 |
|---|---|
| SMILES | C1=CC=C(C=C1)/C=C/C(=O)NC2=NC=C(C=C2)Cl |
| InChIKey | VFPYFCBYQRAYFS-RMKNXTFCSA-N |
Product Overview
N-(5-chloro-2-pyridinyl)-3-phenylacrylamide (CAS 100622-76-2), with molecular formula C14H11ClN2O and molecular weight 258.06 g/mol. IUPAC: (E)-N-(5-chloro-2-pyridinyl)-3-phenylprop-2-enamide.
Chemical Property Profile of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide
Property Insights of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide
The XLogP value of 3.1 indicates that N-(5-chloro-2-pyridinyl)-3-phenylacrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.0 Ų, N-(5-chloro-2-pyridinyl)-3-phenylacrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-chloro-2-pyridinyl)-3-phenylacrylamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide?
The CAS number of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide is 100622-76-2.
What is the molecular formula of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide?
The molecular formula of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide is C14H11ClN2O.
What is the molecular weight of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide?
The molecular weight of N-(5-chloro-2-pyridinyl)-3-phenylacrylamide is 258.06 g/mol.
Where can I buy N-(5-chloro-2-pyridinyl)-3-phenylacrylamide?
You can request a quote for N-(5-chloro-2-pyridinyl)-3-phenylacrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-chloro-2-pyridinyl)-3-phenylacrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-chloro-2-pyridinyl)-3-phenylacrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.