![N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/1005/1005585-82-9.webp)
N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 1005585-82-9) is a chemical compound with molecular formula C24H22N6OS and molecular weight 442.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3,5-dimethyl-1-(2-methylbenzyl)-1H-pyrazol-4-yl]-7-(2-thienyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-[3,5-dimethyl-1-(2-methylbenzyl)-1H-pyrazol-4-yl]-7-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
| Molecular Formula | C24H22N6OS |
|---|---|
| Molecular Weight | 442.16 g/mol |
| LogP | 4.88016 |
| Topological Polar Surface Area | 77.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 442.1576 |
| Heavy Atoms | 32 |
| Complexity | 1430.5153 |
Chemical Identifiers
| CAS Number | 1005585-82-9 |
|---|---|
| SMILES | CC1=CC=CC=C1CN2C(=C(C(=N2)C)NC(=O)C3=C4N=CC=C(N4N=C3)C5=CC=CS5)C |
Product Overview
N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 1005585-82-9), with molecular formula C24H22N6OS and molecular weight 442.16 g/mol. IUPAC: N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 4.88016 indicates that N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.11 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide is 1005585-82-9.
What is the molecular formula of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide is C24H22N6OS.
What is the molecular weight of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide is 442.16 g/mol.
Where can I buy N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-[3,5-dimethyl-1-[(2-methylphenyl)methyl]pyrazol-4-yl]-7-thiophen-2-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.