![4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one structure](/static/products/1005/1005093-36-6.webp)
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one
概要：4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one（CAS 1005093-36-6）是一种化学化合物，分子式为C18H15F5N2O4S，分子量为450.07 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one
又称：4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one, F1079-0246, 4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophen-2-ylcarbonyl)-6-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one, 4-(4-(difluoromethoxy)phenyl)-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)tetrahydropyrimidin-2(1H)-one
| 分子式 | C18H15F5N2O4S |
|---|---|
| 分子量 | 450.07 g/mol |
| LogP | 3.7956 |
| 拓扑极性表面积 | 78.87 Ų |
| 氢键供体数 | 2 |
| 氢键受体数 | 5 |
| 可旋转键数 | 5 |
| 精确质量 | 450.06726 |
| 重原子数 | 30 |
| 复杂度 | 919.658 |
化学标识符
| CAS 编号 | 1005093-36-6 |
|---|---|
| SMILES | CN1C(=O)NC(C(C1(C(F)(F)F)O)C(=O)C2=CC=CS2)C3=CC=C(C=C3)OC(F)F |
产品概述
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one（CAS 1005093-36-6），分子式为C18H15F5N2O4S，分子量为450.07 g/mol。IUPAC名：4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one。
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one化学性质概览
属性洞察：4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的XLogP值为3.7956，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为78.87 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one有2个氢键供体和5个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的CAS号是多少？
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的CAS号为1005093-36-6。
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的分子式是什么？
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的分子式为C18H15F5N2O4S。
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的分子量是多少？
4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的分子量为450.07 g/mol。
在哪里可以购买4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one？
您可以直接向科弘生物询价4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one的定制合成服务？
是的，科弘生物提供4-[4-(difluoromethoxy)phenyl]-6-hydroxy-1-methyl-5-(thiophene-2-carbonyl)-6-(trifluoromethyl)-1,3-diazinan-2-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。