4-硝基苯肼 structure

4-硝基苯肼

TL;DR: 4-硝基苯肼 (CAS 100-16-3) is a chemical compound with molecular formula C21H25N3O3S and molecular weight 399.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-硝基苯肼

6-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-2-ol

Also Known As: 7-Hydroxy Quetiapine, 7-HYDROXYQUETIAPINE, 7-Hydroxy ICI 204636, ICI 214227, MSK10224-100M

CAS: 100-16-3
Molecular Formula C21H25N3O3S
Molecular Weight 399.16 g/mol
LogP 1.8
Topological Polar Surface Area 93.8 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 399.16165
Heavy Atoms 28
Complexity 527.0

Chemical Identifiers

CAS Number 100-16-3
SMILES C1CN(CCN1CCOCCO)C2=NC3=C(C=C(C=C3)O)SC4=CC=CC=C42
InChIKey VEGVCHRFYPFJFO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (29 patents)

Product Overview

4-硝基苯肼 (CAS 100-16-3), with molecular formula C21H25N3O3S and molecular weight 399.16 g/mol. IUPAC: 6-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]benzo[b][1,4]benzothiazepin-2-ol.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-硝基苯肼

XLogP
1.8
TPSA (Topological Polar Surface Area)
93.8
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
28
Complexity
527.0
Exact Mass
399.16165
Monoisotopic Mass
399.16165
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-硝基苯肼

The XLogP value of 1.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-硝基苯肼. The TPSA of 93.8 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-硝基苯肼. Following Lipinski's Rule of Five, 4-硝基苯肼 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-硝基苯肼?

The CAS number of 4-硝基苯肼 is 100-16-3.

What is the molecular formula of 4-硝基苯肼?

The molecular formula of 4-硝基苯肼 is C21H25N3O3S.

What is the molecular weight of 4-硝基苯肼?

The molecular weight of 4-硝基苯肼 is 399.16 g/mol.

Where can I buy 4-硝基苯肼?

You can request a quote for 4-硝基苯肼 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-硝基苯肼?

Yes, KEHONG BIO provides custom synthesis services for 4-硝基苯肼 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?